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Levitra 40 mg is an effective medication used for the treatment of erectile dysfunction. Vardenafil in Levitra helps to regulate the level of cGMP, on the one hand, by the synthesis of guanylate cyclase, and on the other hand, by the degradation (splitting) of cGMP by hydrolysis of PDE. By blocking PDE-5, which is involved in the breakdown of cGMP, vardenafil helps to enhance the local action of endogenous nitric oxide (NO) in the cavernous bodies during sexual stimulation. Increasing the level of cGMP due to inhibition of PDE-5 leads to the relaxation of the smooth muscles of the cavernous bodies and an increase in blood flow into them.
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